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<table width="100%" summary="page for polyps"><tr><td>polyps</td><td style="text-align: right;">R Documentation</td></tr></table>

<h2> Familial Andenomatous Polyposis </h2>

<h3>Description</h3>

<p>Data from a placebo-controlled trial of a non-steroidal anti-inflammatory  
drug in the treatment of familial andenomatous polyposis (FAP).
</p>


<h3>Usage</h3>

<pre>data("polyps")</pre>


<h3>Format</h3>

<p>A data frame with 20 observations on the following 3 variables.
</p>

<dl>
<dt><code>number</code></dt><dd><p>number of colonic polyps at 12 months.</p>
</dd>
<dt><code>treat</code></dt><dd><p>treatment arms of the trail, a factor with 
levels <code>placebo</code> and <code>drug</code>.</p>
</dd>
<dt><code>age</code></dt><dd><p>the age of the patient.</p>
</dd>
</dl>



<h3>Details</h3>

<p>Giardiello et al. (1993) and Piantadosi (1997) describe the
results of a placebo-controlled trial of a non-steroidal anti-inflammatory  
drug in the treatment of familial andenomatous polyposis (FAP). 
The trial was halted after a planned interim analysis had suggested
compelling evidence in favour of the treatment. 
Here we are interested in assessing whether the number of colonic polyps at 
12 months is related to treatment and age of patient.
</p>


<h3>Source</h3>

<p>F. M. Giardiello, S. R. Hamilton, A. J. Krush, S. Piantadosi, L. M. Hylind,
P. Celano, S. V. Booker, C. R. Robinson and G. J. A. Offerhaus (1993), 
Treatment of colonic and rectal adenomas with sulindac 
in familial adenomatous polyposis. <em>New England Journal of Medicine</em>,
<b>328</b>(18), 1313&ndash;1316.
</p>
<p>S. Piantadosi (1997), <em>Clinical Trials: A Methodologic Perspective</em>.
John Wiley \&amp; Sons, New York.
</p>


<h3>Examples</h3>

<pre>

  data("polyps", package = "HSAUR")
  plot(number ~ age, data = polyps, pch = as.numeric(polyps$treat))
  legend(40, 40, legend = levels(polyps$treat), pch = 1:2, bty = "n")

</pre>


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